HBsAg Mutants Clustered Mainly Outside of “a” Determinant in Chronic Carriers From Azarbayjan Province, Iran
نویسندگان
چکیده
منابع مشابه
hbsag mutants clustered mainly outside of “a” determinant in chronic carriers from azarbayjan province, iran
conclusions the distribution of amino acid mutations as well as the ratio between missense and silent nucleotide mutations (dn/ds) showed that a narrowly focused immune pressure had already been on the surface protein (especially ctl epitopes) which led to the emergence of escape mutants in these patients who were in tolerance phase of chronicity. materials and methods the surface genes from 17...
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Abstract Background: Naturally occurred hepatitis B virus (HBV) with surface mutations in a variety of chronic hepatitis B (CHB) patients who have received no vaccine or HBIG bearing substitutions in surface protein, have been reported. Objectives: Current knowledge concerning the prevalence of these naturally occurring surface antigen mutations among Iranian carriers is limited. Patients and M...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Microbiology
سال: 2013
ISSN: 2008-3645,2008-4161
DOI: 10.5812/jjm.6570